Liverpool vs Atletico Madrid preview, team news, lineups and odds

The Reds enter in stellar form with four consecutive wins, most recently defeating Burnley 1:0.

Atletico arrive with mixed results, having beaten Villarreal 2:0 but drawing their two previous LaLiga matches. This clash pits Liverpool's perfect Premier League start against Simeone's tactically disciplined Atletico side.

Liverpool are set to host Atletico Madrid in a highly anticipated Champions League clash at Anfield on September 17, 2025, with kickoff scheduled for 20:00 local time. The match, which will be officiated by Italian referee Maurizio Mariani, marks the first round of the prestigious European competition for both sides.

This encounter brings together two of Europe's elite clubs as they begin their Champions League campaigns, with Liverpool looking to leverage their home advantage against Diego Simeone's tactically astute Atletico Madrid side.

Liverpool enter this Champions League fixture in exceptional form, having won their last four competitive matches. The Reds secured a 1:0 victory against Burnley on September 14 in the Premier League, following a narrow 1:0 win over Arsenal on August 31. Their impressive run also includes a thrilling 3:2 away victory against Newcastle United on August 25 and a high-scoring 4:2 triumph over AFC Bournemouth on August 15.

Their only non-victory in recent matches was a 2:2 draw with Crystal Palace in the Community Shield on August 10. Atletico Madrid, meanwhile, come into this match with mixed recent results.

They defeated Villarreal 2:0 in their most recent LaLiga fixture on September 13, but previously recorded consecutive 1:1 draws against Deportivo Alaves and Elche. The Spanish side suffered a 2:1 defeat to Espanyol on August 17, though they did secure a convincing 2:0 friendly win over Newcastle United on August 9.